Variant calling
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In this problem set, you’re given DNA sequencing data that, when analyzed by mapping reads and calling variants, reveals a secret DNA message. Here’s a decoder based on Church et al. that decodes DNA sequences stored in the file secret:

For example, try:

  • echo "ATGAGACTCTGGACTTCGTCGGGAAATAAGGTATGTATAA" > secret
  • echo "CTGGCTCCCTTCGAAAAGGATCATAGTTAAGT" > secret
  • echo "CTGAATTCCGGTCGCTCGGCTGTCACTGGTTG" > secret
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